Dozed biophysical influences stabilize the bone remodeling markers after unloaded induced osteopenia

1Berezovskii, VA, 1Litovka, IG, 1Kostyuchenko, AS
1Bogomoletz Institute of Physiology of the National Academy of Sciences of Ukraine, Kyiv, Ukraine
Kosm. nauka tehnol. 2005, 11 ;(1-2):093-097
Publication Language: Ukrainian
The 28-day hind limb unloading for 56 young rat-males causes negative changes of physiological and biochemical markers of the bone remodeling, like in microgravitation and hypokinesia conditions. A dozed oxygen deprivation influence in modes of 10/10 and 10/20-min eliminates completely the negative shifts in the glyeo-saminoglican concentrations, normalizes the activity of the alkaline phosphatase, acid phosphatase, tartratresistant acid phosphatase and other markers of the bone remodeling. Periodic inhalation of gas mixture with oxygen reduced to 10 "/„ can either partially or totally compensate the oppression of bone remodeling for persons with sedentary life and insufficient volume of physical load.
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