Features of plant cell cycle regulation under altered gravity conditions
|1Artemenko, OA |
1Institute of Botany of the National Academy of Science of Ukraine, Kyiv, Ukraine
|Kosm. nauka tehnol. 2015, 21 ;(5):108–112|
|Section: Space Life Sciences|
|Publication Language: Ukrainian|
Cyclins and cyclin-dependent kinases (CDK) are main regulators of the cell cycle of eukaryotes. It’s assumes a significant change of their level in cells under microgravity conditions and by other physical factors actions. The clinorotation use enables to determine the influence of gravity on the simulated events in a cell during the cell cycle — exit from the state of quiet stage and propagation through presynthetic phase (G1) and DNA synthesis phase (S) of the cell cycle. For the clinorotation effect study on a cell proliferation activity is the necessary study of molecular mechanisms of the cell cycle regulation and development of plants under altered gravity conditions. The activity of cyclin D, which is responsible for the events of the cell cycle in presynthetic phase can be controlled by the action of endogenous as well as exogenous factors, but clinorotation is one of the factors that influence on genes expression that regulate the cell cycle. This data can be used as a model for a further research on cyclin — CDK complex for study molecular mechanisms of regulation of growth and proliferation. In this investigation we tried to summarize and analyze both bibliographic sources and our own data as for the main regulators of the cell cycle in altered gravity conditions.
|Keywords: cell cycle, clinorotation, cyclin-depending kinases, cyclins, gravysensitive, plant|
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