Effect of hypergravity stress on gaseous exchange and survival of young and old guinea pigs

1Muradian, Kh.K, 2Timchenko, AN
1State Institution "D.F.Chebotarov Institute of Gerontology of the National Academy of Medical Sciences of Ukraine", Kyiv, Ukraine
2State Institution "Institute of Gerontology im.D.F.Chebotarova National Academy of Medical Sciences of Ukraine", Kyiv, Ukraine
Kosm. nauka tehnol. 1999, 5 ;(4):28–30
https://doi.org/10.15407/knit1999.04.028
Section: Space Life Sciences
Publication Language: Russian
Abstract: 
Hypergravity tolerance decreases in aging Guinea pigs, the range being lower than in other studied species of laboratory mammals −mice, hamsters, and rats. Moreover, for the gaseous exchange rate and body temperature, the decline during the stress is not charac­teristic for Guinea pigs of the both age groups, in contrast to other species. In general, hypergravity tolerance of Guinea pigs seems more similar to that of humans, and Guinea pigs could be more appropriate experimental models.
Keywords: appropriate experimental models, hypergravity stress, space life
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